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Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma.

Edgar G KozlovaHsin-Hui HuangOpeyemi A JagedeKevin TuballesDiane M Del ValleGeoffrey KellyManishkumar PatelHui XieJocelyn HarrisKimberly ArguetaKai NieVanessa BarcessatRadim MoravecJennifer AltreuterDzifa Yawa DuoseBrad S KahlStephen M AnsellJoyce YuEthan CeramiJames R LindsayIgnacio I WistubaSeunghee Kim-SchulzeCatherine S DiefenbachSacha Gnjatic
Published in: Cancer research communications (2024)
Identification of multi-omic immune markers from peripheral blood may help elucidate resistance mechanisms to checkpoint inhibitor and antibody-drug conjugate combinations with potential implications for treatment decisions in relapsed HL.
Keyphrases
  • hodgkin lymphoma
  • peripheral blood
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • dna damage
  • gene expression
  • diffuse large b cell lymphoma
  • combination therapy
  • multiple myeloma
  • risk assessment
  • climate change