Sensitivity and specificity of indocyanine green near-infrared fluorescence imaging in detection of metastatic lymph nodes in colorectal cancer: Systematic review and meta-analysis.
Sameh Hany EmileHossam ElfekiMostafa ShalabyAhmad SakrPierpaolo SileriSøren LaurbergSteven D WexnerPublished in: Journal of surgical oncology (2017)
This review aimed to determine the overall sensitivity and specificity of indocyanine green (ICG) near-infrared (NIR) fluorescence in sentinel lymph node (SLN) detection in Colorectal cancer (CRC). A systematic search in electronic databases was conducted. Twelve studies including 248 patients were reviewed. The median sensitivity, specificity, and accuracy rates were 73.7, 100, and 75.7. The pooled sensitivity and specificity rates were 71% and 84.6%. In conclusion, ICG-NIR fluorescence is a promising technique for detecting SLNs in CRC.
Keyphrases
- fluorescence imaging
- sentinel lymph node
- lymph node
- photodynamic therapy
- end stage renal disease
- neoadjuvant chemotherapy
- early stage
- structural basis
- ejection fraction
- newly diagnosed
- small cell lung cancer
- single molecule
- prognostic factors
- randomized controlled trial
- loop mediated isothermal amplification
- peritoneal dialysis
- clinical trial
- drug delivery
- machine learning
- patient reported outcomes
- deep learning
- study protocol
- phase iii
- patient reported
- double blind
- locally advanced