Subject satisfaction and psychological well-being with escalating abobotulinumtoxinA injection dose for the treatment of moderate to severe glabellar lines.

Steven DayanJohn JosephAmir MoradiZ Paul LorencKyle ColemanGlynis AblonJoely KaufmanSue Ellen CoxAndrew CampbellGirish MunavalliInna Prygova

Published in: Journal of cosmetic dermatology (2022)

A single ABO treatment (dosed at 50-125 U) provided significant and sustained improvements in glabellar line severity over durations up to 36 weeks, versus placebo. Treatment satisfaction was high with all doses. Participants reported natural and youthful appearance, alongside improvements in psychological well-being.

Keyphrases

randomized controlled trial
clinical trial
combination therapy
physical activity
sleep quality
smoking cessation
replacement therapy
gestational age
patient reported
finite element