Do Liquid Nitrogen-treated Tumor-bearing Nerve Grafts Have the Capacity to Regenerate, and Do They Pose a Risk of Local Recurrence? A Study in Rats.
Hirotaka YonezawaNorio YamamotoKatsuhiro HayashiAkihiko TakeuchiShinji MiwaKentaro IgarashiSei MorinagaYohei AsanoShiro SaitoKaoru TadaTakayuki NojimaHiroyuki TsuchiyaPublished in: Clinical orthopaedics and related research (2022)
A frozen nerve autograft has a similar regenerative potential to that of a nerve autograft. Although the findings in a rat model do not guarantee efficacy in humans, if they are substantiated by large-animal models, clinical trials will be needed to evaluate the efficacy of tumor-bearing frozen nerve grafts in humans.