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Metal-Organic Framework and Hydrogel Based Strategy as a Universal First-Aid Treatment of Three Different Typical Snake Bites.

Ruolei LiFei CaoYutong ChenPeixin ZhangChunhong HuangHongbo XinJun WangXiaolei Wang
Published in: ACS biomaterials science & engineering (2019)
Snake bite envenoming is a worldwide problem which affects the health and safety of the public. The classical antivenom methods are difficult to be used immediately and accurately. Based on this situation, a new metal-organic framework and hydrogel based first-aid treatment was first set up in this study as a facile, economic, effective, and universal alternative strategy. According to the subsequent in vitro and in vivo experiments, this dual effective (block and absorption) strategy was proven to be useful in dealing with three different representative snake venoms (Bungarus fasciatus, Protobothrops mucrosquamatus, and cobra venom).
Keyphrases
  • metal organic framework
  • healthcare
  • drug delivery
  • mental health
  • public health
  • emergency department
  • cross sectional
  • hyaluronic acid
  • gold nanoparticles
  • reduced graphene oxide
  • replacement therapy