Is nestin a diagnostic marker for combined hepatocellular-cholangiocarcinoma?

Published in: Histopathology (2022)

Nestin may be a useful diagnostic marker for a specific subgroup of cHCC-CCA and small duct-type iCCA associated with CLC components, p53 mutations and multiple genetic alterations, which are related to stemness and multipotent differentiation.

Keyphrases

stem cells
epithelial mesenchymal transition
genome wide
gene expression
randomized controlled trial
copy number
cancer stem cells
open label
placebo controlled