Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts.

Junbin ChenHidayat UllahZhongdaixi ZhengXiangfu GuChuhong SuLingyu XiaoXinglong WuFei XiongQing LiLongying Zha

Published in: BMC complementary medicine and therapies (2020)

Soyasaponins can reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts. This study provides novel understanding about the anti-inflammatory mechanism of soyasaponins.

Keyphrases

toll like receptor
poor prognosis
inflammatory response
nuclear factor
oxidative stress
immune response
anti inflammatory
signaling pathway
binding protein
long non coding rna