Pipamperone Population Pharmacokinetics Related to Effectiveness and Side Effects in Children and Adolescents.
Sanne Maartje KloosterboerKarin M EgbertsBrenda C M de WinterTeun van GelderManfred GerlachManon H J HillegersGwen C DielemanSoma BahmanyCatrien G ReichartEmma van DaalenMirjam E J KouijzerBram DierckxBirgit C P KochPublished in: Clinical pharmacokinetics (2021)
Our findings suggest that pipamperone therapeutic reference ranges may be lower for children with behavioral problems than recommended for adults with psychotic symptoms (100-400 µg/L). When dosing pipamperone in children and adolescents, bodyweight should be taken into account.