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In silico benchmarking of metagenomic tools for coding sequence detection reveals the limits of sensitivity and precision.

Jonathan Louis GolobSamuel Schwartz Minot
Published in: BMC bioinformatics (2020)
Our benchmarking approach reveals the trade-offs of assembly versus alignment-based approaches and the relative performance of specific implementations when one wishes to extract the protein coding capacity of microbial communities.
Keyphrases
  • oxidative stress
  • amino acid
  • molecular docking
  • antibiotic resistance genes
  • real time pcr
  • binding protein
  • microbial community
  • quantum dots
  • wastewater treatment