Tigecycline Pharmacokinetic and Pharmacodynamic Profile in Patients with Chronic Obstructive Pulmonary Disease Exacerbation.

Maria Kipourou Olga BegouKaterina ManikaGeorgios IsmailosPaschalina KontouGeorgia Pitsiou Helen G GikaIoannis Kioumis

Published in: Antibiotics (Basel, Switzerland) (2023)

Our findings support the clinical effectiveness of tigecycline against commonly causative bacteria in COPD exacerbations and highlight its sufficient lung penetration in pulmonary infections of moderate severity.

Keyphrases

chronic obstructive pulmonary disease
acinetobacter baumannii
klebsiella pneumoniae
lung function
randomized controlled trial
pulmonary hypertension
systematic review
multidrug resistant
drug resistant
high intensity
cystic fibrosis
pseudomonas aeruginosa
escherichia coli
air pollution
respiratory failure