Low-dose IL-2 in children with recently diagnosed type 1 diabetes: a Phase I/II randomised, double-blind, placebo-controlled, dose-finding study.

Michelle RosenzwajgRanda SaletRoberta LorenzonNicolas TchitchekAlexandra RouxClaude BernardJean-Claude CarelCaroline StoreyMichel PolakJacques BeltrandChloé AmouyalAgnès HartemannPierre CorbeauEric VicautCecile BibalPierre BougnèresTu-Anh TranDavid Klatzmann

Published in: Diabetologia (2020)

Assistance Publique-Hôpitaux de Paris, Investissements d'Avenir programme (ANR-11-IDEX-0004-02, LabEx Transimmunom and ANR-16-RHUS-0001, RHU iMAP) and European Research Council Advanced Grant (FP7-IDEAS-ERC-322856, TRiPoD).

Keyphrases

placebo controlled
double blind
study protocol
low dose
type diabetes
clinical trial
phase ii
phase iii
phase ii study
young adults
open label
high dose
randomized controlled trial
insulin resistance
cardiovascular disease
squamous cell carcinoma
glycemic control
metabolic syndrome