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Identification of PsA phenotypes with machine learning analytics using data from two phase III clinical trials of guselkumab in a bio-naïve population of patients with PsA.

Pascal RichetteMarijn VisSarah OhrndorfWilliam TillettJulio RamírezMarlies NeuholdMichel van SpeybroeckElke TheanderWim NoelMiriam ZimmermannMay ShawiAlexa KollmeierAlen Zabotti
Published in: RMD open (2023)
Unsupervised machine learning identified eight PsA phenotype clusters with significant differences in demographics, clinical features and treatment responses. In the future, such data could help support individualised treatment decisions.
Keyphrases
  • machine learning
  • big data
  • prostate cancer
  • clinical trial
  • phase iii
  • radical prostatectomy
  • artificial intelligence
  • randomized controlled trial
  • combination therapy
  • replacement therapy