Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD).
Sivasubramanium BhavaniChu-Lin TsaiSarah PerusichSean HesselbacherHarvey CoxsonLavannya PanditDavid B CorryFarrah KheradmandPublished in: American journal of respiratory and critical care medicine (2016)
The rate of emphysema progression quantified by CT scans among ever-smokers was highly variable; clinical factors and biomarkers explained only some of the variability. Aggressive clinical care that targets active smokers with autoreactive T cells and low BMI may temporize progression of emphysema.