Single-cell analysis of white adipose tissue reveals the tumor-promoting adipocyte subtypes.

Si-Qing LiuDing-Yuan ChenBei LiZhi-Jie GaoHong-Fang FengXin YuZhou LiuYuan WangWen-Ge LiSi SunSheng-Rong SunQi Wu

Published in: Journal of translational medicine (2023)

Our results provide a novel understanding of TAME at the single-cell level. Based on our findings, several adipocyte subtypes have negative impact on prognosis. These cancer-associated adipocytes may serve as key prognostic predictor and potential targets for treatment in the future.

Keyphrases

adipose tissue
single cell
insulin resistance
rna seq
high fat diet
high throughput
current status
fatty acid
risk assessment
human health
high fat diet induced
climate change