Metformin as a prophylactic treatment of gestational diabetes in pregnant patients with pregestational insulin resistance: A randomized study.

Enrique Valdés Alvaro Sepúlveda-MartínezPaula CandiaNancy AbusadaRodrigo OrellanaBárbara ManukianEduardo Cuellar

Published in: The journal of obstetrics and gynaecology research (2017)

The use of MTF is not effective in prevention of GDM in populations with PIR. The use of MTF shows a significantly higher frequency of drug intolerance than placebo.

Keyphrases

insulin resistance
adipose tissue
pregnant women
type diabetes
metabolic syndrome
randomized controlled trial
emergency department
clinical trial
pregnancy outcomes
phase iii
adverse drug
high fat diet induced
smoking cessation