A Galectin-9-Driven CD11c high Decidual Macrophage Subset Suppresses Uterine Vascular Remodeling in Preeclampsia.

Yanhong LiYifei SangYunjian ChangChunfang XuYikong LinYao ZhangPhilip C N ChiuWilliam Shu Biu YeungHaisheng ZhouNingzheng DongLing XuJiajia ChenWeijie ZhaoLu LiuDi Yu Xingxing ZangJiangfeng YeJinying YangQingyu Wu Da-Jin LiLigang WuMei-Rong Du

Published in: Circulation (2024)

dMφ activated by increased galectin-9 from trophoblasts suppresses uterine spiral artery remodeling, contributing to preeclampsia. Increased circulating galectin-9 may be a biomarker for preeclampsia prediction and intervention.

Keyphrases

early onset
signaling pathway
pregnancy outcomes
randomized controlled trial
metabolic syndrome
glycemic control