HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells.
Ian A TamargoKyung In BaekChenbo XuDong Won KangYerin KimAitor AnduezaDarian WilliamsCatherine DemosNicolas Villa-RoelHanjoong JoChristian ParkRachel ChoiJanie JohnsonSeowon ChangPaul KimSheryl TanKiyoung JeongShoutaro TsujiHanjoong JoPublished in: Circulation (2023)
Our findings indicate that HEG1 is a novel mediator of atheroprotective endothelial responses to flow and a potential therapeutic target.