Poor Endometrial Proliferation After Clomiphene is Associated With Altered Estrogen Action.
Leah Hawkins BresslerMarc A FritzSan Pin WuLingwen YuanSuzanna KaferTianyuan WangFrancesco J DeMayoSteven L YoungPublished in: The Journal of clinical endocrinology and metabolism (2021)
Women with suboptimal endometrial thickness after clomiphene exhibit aberrant ER expression patterns, architectural changes, and altered gene and protein expression suggesting reduced proliferation and angiogenesis in the setting of increased inflammation.
Keyphrases
- polycystic ovary syndrome
- signaling pathway
- estrogen receptor
- endometrial cancer
- poor prognosis
- oxidative stress
- endothelial cells
- copy number
- optical coherence tomography
- vascular endothelial growth factor
- insulin resistance
- type diabetes
- endoplasmic reticulum
- gene expression
- dna methylation
- metabolic syndrome
- genome wide identification