Endogenous DHEAS Is Causally Linked With Lumbar Spine Bone Mineral Density and Forearm Fractures in Women.
Johan QuesterMaria NethanderAnna ErikssonClaes OhlssonPublished in: The Journal of clinical endocrinology and metabolism (2022)
Genetically predicted serum DHEAS increases LS-BMD and decreases forearm fracture risk in women. Based on the results of the present study and previous randomized controlled trials of DHEA treatment, we propose that both endogenous adrenal-derived DHEA(S) and pharmacological DHEA treatment improve bone health in women.
Keyphrases
- bone mineral density
- polycystic ovary syndrome
- postmenopausal women
- randomized controlled trial
- pregnancy outcomes
- healthcare
- public health
- cervical cancer screening
- mental health
- type diabetes
- clinical trial
- insulin resistance
- pregnant women
- climate change
- health information
- social media
- soft tissue
- meta analyses
- smoking cessation