Risk factors affecting prognosis in metachronous liver metastases from WHO classification G1 and G2 gastroenteropancreatic neuroendocrine tumors after initial R0 surgical resection.
Yang LvXu HanXue-Feng XuYuan JiYu-Hong ZhouHui-Chuan SunJian ZhouJia FanWen-Hui LouCheng HuangPublished in: BMC cancer (2019)
A higher Ki-67 index in metastases compared to primary tumor was an independent factor for poor prognosis. Local treatment was associated with prolonged survival of hepatic metastatic GEP-NET patients. Optimal treatment strategies based on clinicopathological characteristics should be developed.
Keyphrases
- poor prognosis
- neuroendocrine tumors
- liver metastases
- long non coding rna
- end stage renal disease
- squamous cell carcinoma
- newly diagnosed
- ejection fraction
- small cell lung cancer
- machine learning
- prognostic factors
- peritoneal dialysis
- radiation therapy
- neoadjuvant chemotherapy
- patient reported outcomes
- combination therapy
- replacement therapy