DNA methylation pattern changes following a short-term hypocaloric diet in women with obesity.
C F NicolettiC Cortes-OliveiraN Y NoronhaM A S PinhelW S DantasA JácomeJulio Sérgio MarchiniB GualanoA B CrujeirasC B NoninoPublished in: European journal of clinical nutrition (2020)
A short-term hypocaloric intervention in patients with severe obesity partially restored the obesity-related DNA methylation pattern. Thus, the full change of obesity-related DNA methylation patterns could be proportional to the weight-loss rate in these patients after dietary interventions.
Keyphrases
- weight loss
- dna methylation
- bariatric surgery
- insulin resistance
- metabolic syndrome
- roux en y gastric bypass
- weight gain
- high fat diet induced
- type diabetes
- genome wide
- gene expression
- gastric bypass
- end stage renal disease
- randomized controlled trial
- physical activity
- ejection fraction
- glycemic control
- newly diagnosed
- peritoneal dialysis
- chronic kidney disease
- skeletal muscle
- body mass index
- drug induced
- patient reported