The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris.
Klara JunkerGustavo Bravo RuizAlexander LorenzLouise WalkerNeil A R GowJürgen WendlandPublished in: Scientific reports (2018)
Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, we show that the mycoparasitic yeast Saccharomycopsis schoenii efficiently kills both sensitive and multi-drug resistant isolates of C. auris belonging to the same clade, as well as clinical isolates of other pathogenic species of the Candida genus suggesting novel approaches for biocontrol.
Keyphrases
- drug resistant
- candida albicans
- multidrug resistant
- acinetobacter baumannii
- global health
- biofilm formation
- end stage renal disease
- intensive care unit
- ejection fraction
- chronic kidney disease
- newly diagnosed
- public health
- healthcare
- physical activity
- heavy metals
- saccharomyces cerevisiae
- pseudomonas aeruginosa
- peritoneal dialysis
- escherichia coli
- patient reported outcomes
- acute respiratory distress syndrome