Spatiotemporal Dynamics of Neuroinflammation Relate to Behavioral Recovery in Rats with Spinal Cord Injury.
Chaoqi MuJamie L ReedFeng WangM Noor TantawyJohn C GoreLi Min ChenPublished in: Molecular imaging and biology (2023)
The detection of dynamic spatiotemporal features of neuroinflammation progression underscores the importance of considering their timings and locations for neuroprotective and anti-inflammatory therapies. The availability of noninvasive MRI indices of neuroinflammation may facilitate clinical trials aimed at treatments that promote recovery after SCI.
Keyphrases
- cerebral ischemia
- lipopolysaccharide induced
- lps induced
- traumatic brain injury
- clinical trial
- cognitive impairment
- anti inflammatory
- inflammatory response
- spinal cord injury
- subarachnoid hemorrhage
- magnetic resonance imaging
- blood brain barrier
- brain injury
- contrast enhanced
- loop mediated isothermal amplification
- randomized controlled trial
- label free
- diffusion weighted imaging
- real time pcr
- phase iii
- open label