Reasons for Discordance between 68 Ga-PSMA-PET and Magnetic Resonance Imaging in Men with Metastatic Prostate Cancer.
Jade WangElisabeth O'DwyerJuana Martinez ZuloagaKritika SubramanianJim C HuYuliya S JhanwarHimanshu NagarArindam RoyChoudhuryJohn BabichSandra Huicochea CastellanosJoseph R OsborneDaniel J A MargolisPublished in: Cancers (2024)
Notably, almost 50% of the cases, including most lymph node metastases, were anatomically normal using standard criteria. This suggests that current anatomic criteria for evaluating prostate cancer lymph node metastases are not ideal, and there is a need for improved criteria. In addition, 32% of cases involved some element of human interpretive error, and, therefore, improving reader training may lead to more accurate results.