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GATA3 staining in primary cutaneous apocrine cribriform carcinoma: Usefulness to differentiate it from breast cancer metastasis.

Mar Llamas VelascoYosmar C Pérez-GónzalezEsteban DaudénArno Rütten
Published in: Journal of cutaneous pathology (2018)
Even though GATA3 expression has been reported in many benign and malignant adnexal tumors (mostly of sebaceous, follicular, and apocrine differentiation), as well as in many other neoplasms, GATA3 staining to differentiate PCACC from skin breast cancer metastasis has a high negative predictive value. A positive GATA3 staining in this context should permit one to rule out PCACC with a high level of confidence.
Keyphrases
  • transcription factor
  • flow cytometry
  • poor prognosis
  • soft tissue
  • long non coding rna
  • breast cancer risk