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pCREB expression in human tissues from epilepsy surgery.

Dalia De SantisLaura RossiniLaura TassiGiuseppe DidatoGiovanni TringaliMassimo CossuManuela BramerioFrancesco PadelliMaria Cristina RegondiFrancesca ColciaghiEleonora AronicaRoberto SpreaficoRita Garbelli
Published in: Epilepsia (2020)
The present data argue against the reliability of pCREB immunohistochemistry as a marker of epileptic focus but underscores its layer-related expression, suggesting a potential application in the study of malformations of cortical development, a wide range of diseases arising from perturbations of normal brain development.
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