DSC Perfusion MRI-Derived Fractional Tumor Burden and Relative CBV Differentiate Tumor Progression and Radiation Necrosis in Brain Metastases Treated with Stereotactic Radiosurgery.
Frank KuoNathan Norton NgMelanie Hayden GephartErqi L PollomScott G SoltysGordon LiDonald E BornMichael IvPublished in: AJNR. American journal of neuroradiology (2022)
Increased relative CBV and high fractional tumor burden (defined by a threshold relative CBV of ≥1.75) best differentiated tumor from radiation necrosis in subjects with brain metastases treated with stereotactic radiosurgery. Performance of normalized and standardized approaches was similar.