Sustained Surface ICAM-1 Expression and Transient PDGF-B Production by Phorbol Myristate Acetate-Activated THP-1 Cells Harboring Blau Syndrome-Associated NOD2 Mutations.

Mizuho NishiyamaHong-Jin LiIkuo OkafujiAkihiko FujisawaMizue EharaNaotomo KambeFukumi FurukawaNobuo Kanazawa

Published in: Children (Basel, Switzerland) (2021)

Sustained surface ICAM-1 expression and transient PDGF-B production by newly differentiating macrophages harboring mutant NOD2 might play a role in granuloma formation in Blau syndrome.

Keyphrases

poor prognosis
induced apoptosis
smooth muscle
binding protein
vascular smooth muscle cells
cell cycle arrest
long non coding rna
magnetic resonance imaging
endoplasmic reticulum stress
cell death
oxidative stress