Effects of suboptimal adherence of CPAP therapy on symptoms of obstructive sleep apnoea: a randomised, double-blind, controlled trial.
Thomas GaislProtazy RejmerSira ThielSarah R HaileMartin OsswaldMałgorzata RoosKonrad E BlochJohn R StradlingMalcolm KohlerPublished in: The European respiratory journal (2020)
Patients with moderate-to-severe OSA and daytime sleepiness are still getting a substantial benefit from suboptimal CPAP adherence, albeit not as much as they might get if they adhered more. Whether a similar statement can be made for even lower adherence levels remains to be established in future trials.
Keyphrases
- obstructive sleep apnea
- positive airway pressure
- double blind
- sleep quality
- sleep apnea
- clinical trial
- placebo controlled
- study protocol
- open label
- glycemic control
- metabolic syndrome
- high intensity
- randomized controlled trial
- type diabetes
- current status
- bone marrow
- skeletal muscle
- weight loss
- mesenchymal stem cells
- insulin resistance
- smoking cessation