High Effectiveness of Midazolam and Lidocaine in the Treatment of Acute Neonatal Seizures.

José Ramón Castro CondeCandelaria González CampoDesiré González BarriosBeatriz Reyes MillánCandelaria Leticia Díaz GonzálezAlejandro Jiménez Sosa

Published in: Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society (2023)

This retrospective study suggests that the midazolam/lidocaine association could potentially be efficacious in decreasing seizure burden in term neonates with acute seizures. These results would justify testing the midazolam/lidocaine combination as a first-line treatment for neonatal seizures in future clinical trials.

Keyphrases

liver failure
clinical trial
respiratory failure
temporal lobe epilepsy
drug induced
aortic dissection
systematic review
randomized controlled trial
current status
low birth weight
placebo controlled