A feasibility study on yoga's mechanism of action for chronic low back pain: psychological and neurophysiological changes, including global gene expression and DNA methylation, following a yoga intervention for chronic low back pain.

Bandita AdhikariAngela R StarkweatherWanli XuRebecca L AcabchukDivya RameshBright EzeYuxuan YangGee Su YangJoseph WalkerReinhard LaubenbacherCrystal L Park

Published in: Pilot and feasibility studies (2022)

The study supports the feasibility and acceptability of the proposed protocol to test a specific mechanism of action for yoga in individuals with cLBP. These results also support the notion that yoga may operate through our identified psychological and neurophysiologic pathways to influence reduced pain severity and interference.

Keyphrases

dna methylation
gene expression
randomized controlled trial
chronic pain
genome wide
pain management
depressive symptoms
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