Aging effect on sleepiness and apneas severity in patients with obstructive sleep apnea syndrome: a meta-analysis study.
Giannicola IannellaClaudio ViciniAndrea ColizzaGiuseppe MeccarielloAntonella PolimeniAntonio GrecoMarco de VincentiisAndrea de VitoGiovanni CammarotoRiccardo GobbiChiara BelliniElisabetta FirinuStefano PelucchiGiampiero GulottaIrene Claudia ViscontiMilena di LucaGiuseppe MagliuloPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2019)
Meta-analysis showed no statistical (p = 0.8) differences regarding AHI differences emerged from the comparison of the two groups of patients. Elderly patients (> 65 years old) showed less daytime sleepiness, showing a statistical difference in the meta-analysis of data (p = 0.004) CONCLUSION: Although a direct correlation between aging and AHI values would seem to be present, no significant differences in baseline AHI between young (< 65-years-old) and elderly (> 65-years-old) patients emerged in this meta-analysis study. The effects of OSAS on daytime sleepiness seem to be much more prominent in young or middle-aged patients than in elderly patients.
Keyphrases
- obstructive sleep apnea
- end stage renal disease
- systematic review
- middle aged
- newly diagnosed
- ejection fraction
- chronic kidney disease
- positive airway pressure
- sleep quality
- prognostic factors
- peritoneal dialysis
- machine learning
- randomized controlled trial
- depressive symptoms
- case report
- big data
- electronic health record