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Is Saglin a mosquito salivary gland receptor for Plasmodium falciparum?

David A O'BrochtaRobert AlfordRobert HarrellChanna AluvihareAbraham G EappenTao LiSumana ChakravartyB Kim Lee SimStephen L HoffmanChmi-Sika Study Team
Published in: Malaria journal (2019)
The absence of Saglin in the distal lateral lobes of the salivary glands, a primary destination for SPZ, suggests Saglin is not an essential receptor for Plasmodium SPZ. The lack of any correlation between increased Saglin expression in the distal lateral lobes of the salivary glands of transgenic An. stephensi and PfSPZ infection is also consistent with Saglin not being an essential salivary gland receptor for Plasmodium SPZ.
Keyphrases
  • plasmodium falciparum
  • minimally invasive
  • binding protein
  • poor prognosis
  • long non coding rna
  • dengue virus