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Multiple selective sweeps of ancient polymorphisms in and around LTα located in the MHC class III region on chromosome 6.

Michael C CampbellBryan AshongShaolei TengJayla HarveyChristopher N Cross
Published in: BMC evolutionary biology (2019)
Overall, this study identified candidate functional alleles in a biologically-relevant genomic region, and offers new insights into the evolutionary origins of these loci in modern human populations.
Keyphrases
  • genome wide
  • endothelial cells
  • copy number
  • induced pluripotent stem cells
  • dna methylation
  • pluripotent stem cells