Multicenter in vitro thromboelastography and thromboelastometry standardization.
Robert GoggsAntonio BorrelliBenjamin M BrainardGregory R LisciandroArmelle de LaforcadeIsabelle Goy-ThollotKarl E JandreyAnnemarie T KristensenAnnette P N KutterClara B MarschnerBenoît RannouNadja SigristCatherine WaggPublished in: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) (2018)
More variation within and between centers was identified than anticipated, but some parameters such as alpha angle were repeatable and reproducible. Sample types for future multicenter standardization efforts will require further optimization and may need to be adapted separately to each platform. Individual centers using viscoelastic tests for evaluation and management of clinical patients should take steps to minimize preanalytical and analytical sources of variation.