On-therapy impedance-pH monitoring can efficiently characterize PPI-refractory GERD and support treatment escalation.

Marzio FrazzoniLeonardo FrazzoniMentore RibolsiSalvatore RussoRita ConigliaroNicola de BortoliEdoardo Savarino

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2023)

We have defined on-PPI cut-offs of impedance-pH metrics by which comprehensive assessment of impedance-pH tracings, including analysis of PSPW index and MNBI can efficiently characterize PPI-refractory GERD and support treatment escalation.

Keyphrases

open label
clinical trial
magnetic resonance imaging
stem cells
randomized controlled trial
combination therapy
magnetic resonance
mesenchymal stem cells
small molecule
dual energy
cell therapy
study protocol