Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.
Ming Wai YeungSiqi WangYordi J van de VegteOleg V BorisovJessica van SettenHarold SniederNiek VerweijM Abdullah SaidPim van der HarstPublished in: Arteriosclerosis, thrombosis, and vascular biology (2021)
Genome-wide association meta-analyses in >100 000 individuals identified 25 novel loci associated with cIMT providing insights into genes and tissue-specific regulatory mechanisms of proatherosclerotic processes. We found evidence for shared biological mechanisms with cardiovascular diseases.