FOXO1 mitigates the SMAD3/FOXL2C134W transcriptomic effect in a model of human adult granulosa cell tumor.
Christian SecchiPaola BenaglioFrancesca MulasMartina BelliDwayne StupackShunichi ShimasakiPublished in: Journal of translational medicine (2021)
Our transcriptomic data provide novel insights into potential genes (FOXO1 regulated) that could be used as biomarkers of efficacy in aGCT patients.
Keyphrases
- single cell
- transcription factor
- end stage renal disease
- chronic kidney disease
- endothelial cells
- ejection fraction
- signaling pathway
- rna seq
- newly diagnosed
- epithelial mesenchymal transition
- pi k akt
- electronic health record
- cell therapy
- genome wide
- type diabetes
- transforming growth factor
- gene expression
- skeletal muscle
- insulin resistance
- artificial intelligence
- induced pluripotent stem cells
- climate change
- pluripotent stem cells
- patient reported