Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis.
Thais Caroline Dallabona DombroskiJosé Eduardo Peixoto-SantosKarina MacielMunira Muhammad Abdel BaquiTonicarlo Rodrigues VelascoAmerico Ceiki SakamotoJoão Alberto AssiratiCarlos Gilberto CarlottiHélio Rubens MachadoGleice Kelly de SousaKenji HanamuraJoao Pereira LeiteJaderson Costa da CostaAndré Luis Fernandes PalminiEliseu PaglioliLuciano NederRoberto SpreaficoTomoaki ShiraoRita GarbelliAntonio Roberto MartinsPublished in: Epilepsia (2020)
Our results suggest that changes in drebrin-positive spines and drebrin expression in the dentate gyrus of TLE patients are associated with lower seizure frequency, more preserved verbal memory, and a better postsurgical outcome.