CD103 integrin identifies a high IL-10-producing FoxP3+ regulatory T-cell population suppressing allergic airway inflammation.
Sofia TagkareliMaria SalagianniIoanna-Evdokia GalaniMaria ManioudakiEleftherios PavlosKalliopi ThanopoulouEvangelos AndreakosPublished in: Allergy (2021)
Our study identifies a novel regulatory T-cell population, defined by CD103 expression, programmed to prevent exuberant type 2 inflammation and keep homeostasis in the respiratory tract under control. This has important therapeutic implications.