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CD103 integrin identifies a high IL-10-producing FoxP3+ regulatory T-cell population suppressing allergic airway inflammation.

Sofia TagkareliMaria SalagianniIoanna-Evdokia GalaniMaria ManioudakiEleftherios PavlosKalliopi ThanopoulouEvangelos Andreakos
Published in: Allergy (2021)
Our study identifies a novel regulatory T-cell population, defined by CD103 expression, programmed to prevent exuberant type 2 inflammation and keep homeostasis in the respiratory tract under control. This has important therapeutic implications.
Keyphrases
  • respiratory tract
  • genome wide
  • transcription factor
  • poor prognosis
  • oxidative stress
  • regulatory t cells
  • nk cells
  • signaling pathway
  • immune response
  • long non coding rna