Effects of Atypical Antipsychotic Treatment and Resistant Starch Supplementation on Gut Microbiome Composition in a Cohort of Patients with Bipolar Disorder or Schizophrenia.

Stephanie A FlowersNielson T BaxterKristen M WardA Zarina KraalMelvin G McInnisThomas M SchmidtVicki L Ellingrod

Published in: Pharmacotherapy (2019)

These data suggest that AAP treatment is associated with measurable differences in gut microbiota, particularly in female AAP-treated patients in whom reduced species richness was observed. Additionally, variable microbiome responses to resistant starch supplementation were seen, with a significant increase in starch degraders.

Keyphrases

bipolar disorder
end stage renal disease
newly diagnosed
major depressive disorder
chronic kidney disease
ejection fraction
prognostic factors
electronic health record
combination therapy
machine learning
lactic acid
artificial intelligence