Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy.
Yuchen XuRui SongWenjuan ChenKatie StrongDaniel ShreySatyanarayana GedelaStephen F TraynelisGuojun ZhangHongjie YuanPublished in: Annals of clinical and translational neurology (2021)
Our finding contributes to the understanding of the phenotype-genotype correlations of patients with GRIN1 gene variants, provides a molecular mechanism underlying the actions of this variant, and explores therapeutic strategies for treating GRIN1-related neurological conditions.