Stephen F Traynelis (Stephen Traynelis)

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 57

Top Venues

Cellular and molecular life sciences : CMLS

ACS chemical neuroscience

Journal of neurophysiology

Nature

This page only lists publications with an associated author ORCID identifier.

Publications

Tsung-Han Chou, Max Epstein, Russell G Fritzemeier, Nicholas S Akins, Srinu Paladugu, Elijah Z Ullman, Dennis C Liotta, Stephen F Traynelis, Hiro Furukawa
Molecular mechanism of ligand gating and opening of NMDA receptor. Nature 632 (8023) (2024)
Yuchen Xu, Rui Song, Riley E Perszyk, Wenjuan Chen, Sukhan Kim, Kristen L Park, James P Allen, Kelsey A Nocilla, Jing Zhang, Wenshu XiangWei, Anel Tankovic, Ellington D McDaniels, Rehan Sheikh, Ruth K Mizu, Manish M Karamchandani, Chun Hu, Hirofumi Kusumoto, Joseph Pecha, Gerarda Cappuccio, John Gaitanis, Jennifer Sullivan, Vandana Shashi, Slave Petrovski, Robin-Tobias Jauss, Hyun Kyung Lee, Xiuhua Bozarth, David R Lynch, Ingo Helbig, Tyler Mark Pierson, Cornelius F Boerkoel, Scott J Myers, Johannes R Lemke, Timothy A Benke, Hongjie Yuan, Stephen F Traynelis
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Yuchen Xu, Rui Song, Riley E Perszyk, Wenjuan Chen, Sukhan Kim, Kristen L Park, James P Allen, Kelsey A Nocilla, Jing Zhang, Wenshu XiangWei, Anel Tankovic, Ellington D McDaniels, Rehan Sheikh, Ruth K Mizu, Manish M Karamchandani, Chun Hu, Hirofumi Kusumoto, Joseph Pecha, Gerarda Cappuccio, John Gaitanis, Jennifer Sullivan, Vandana Shashi, Slave Petrovski, Robin-Tobias Jauss, Hyun Kyung Lee, Xiuhua Bozarth, David R Lynch, Ingo Helbig, Tyler Mark Pierson, Cornelius F Boerkoel, Scott J Myers, Johannes R Lemke, Timothy A Benke, Hongjie Yuan, Stephen F Traynelis
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Tsung-Han Chou, Max Epstein, Russell G Fritzemeier, Nicholas S Akins, Srinu Paladugu, Elijah Z Ullman, Dennis C Liotta, Stephen F Traynelis, Hiro Furukawa
Molecular mechanism of ligand gating and opening of NMDA receptor. Nature 632 (8023) (2024)
Tue G Banke, Stephen F Traynelis, Andres Barria
Early expression of GluN2A-containing NMDA receptors in a model of fragile X syndrome. Journal of neurophysiology 131 (4) (2024)
Yuchen Xu, Rui Song, Riley E Perszyk, Wenjuan Chen, Sukhan Kim, Kristen L Park, James P Allen, Kelsey A Nocilla, Jing Zhang, Wenshu XiangWei, Anel Tankovic, Ellington D McDaniels, Rehan Sheikh, Ruth K Mizu, Manish M Karamchandani, Chun Hu, Hirofumi Kusumoto, Joseph Pecha, Gerarda Cappuccio, John Gaitanis, Jennifer Sullivan, Vandana Shashi, Slave Petrovski, Robin-Tobias Jauss, Hyun Kyung Lee, Xiuhua Bozarth, David R Lynch, Ingo Helbig, Tyler Mark Pierson, Cornelius F Boerkoel, Scott J Myers, Johannes R Lemke, Timothy A Benke, Hongjie Yuan, Stephen F Traynelis
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Tue G Banke, Stephen F Traynelis, Andres Barria
Early expression of GluN2A-containing NMDA receptors in a model of fragile X syndrome. Journal of neurophysiology 131 (4) (2024)
Tue G Banke, Stephen F Traynelis, Andres Barria
Early expression of GluN2A-containing NMDA receptors in a model of fragile X syndrome. Journal of neurophysiology 131 (4) (2024)
Tue G Banke, Stephen F Traynelis, Andres Barria
Early expression of GluN2A-containing NMDA receptors in a model of fragile X syndrome. Journal of neurophysiology 131 (4) (2024)
Tsung-Han Chou, Max Epstein, Russell G Fritzemeier, Nicholas S Akins, Srinu Paladugu, Elijah Z Ullman, Dennis C Liotta, Stephen F Traynelis, Hiro Furukawa
Molecular mechanism of ligand gating and opening of NMDA receptor. Nature 632 (8023) (2024)
Tue G Banke, Stephen F Traynelis, Andres Barria
Early expression of GluN2A-containing NMDA receptors in a model of fragile X syndrome. Journal of neurophysiology 131 (4) (2024)
Yuchen Xu, Rui Song, Riley E Perszyk, Wenjuan Chen, Sukhan Kim, Kristen L Park, James P Allen, Kelsey A Nocilla, Jing Zhang, Wenshu XiangWei, Anel Tankovic, Ellington D McDaniels, Rehan Sheikh, Ruth K Mizu, Manish M Karamchandani, Chun Hu, Hirofumi Kusumoto, Joseph Pecha, Gerarda Cappuccio, John Gaitanis, Jennifer Sullivan, Vandana Shashi, Slave Petrovski, Robin-Tobias Jauss, Hyun Kyung Lee, Xiuhua Bozarth, David R Lynch, Ingo Helbig, Tyler Mark Pierson, Cornelius F Boerkoel, Scott J Myers, Johannes R Lemke, Timothy A Benke, Hongjie Yuan, Stephen F Traynelis
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Yuchen Xu, Rui Song, Riley E Perszyk, Wenjuan Chen, Sukhan Kim, Kristen L Park, James P Allen, Kelsey A Nocilla, Jing Zhang, Wenshu XiangWei, Anel Tankovic, Ellington D McDaniels, Rehan Sheikh, Ruth K Mizu, Manish M Karamchandani, Chun Hu, Hirofumi Kusumoto, Joseph Pecha, Gerarda Cappuccio, John Gaitanis, Jennifer Sullivan, Vandana Shashi, Slave Petrovski, Robin-Tobias Jauss, Hyun Kyung Lee, Xiuhua Bozarth, David R Lynch, Ingo Helbig, Tyler Mark Pierson, Cornelius F Boerkoel, Scott J Myers, Johannes R Lemke, Timothy A Benke, Hongjie Yuan, Stephen F Traynelis
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Yuchen Xu, Rui Song, Riley E Perszyk, Wenjuan Chen, Sukhan Kim, Kristen L Park, James P Allen, Kelsey A Nocilla, Jing Zhang, Wenshu XiangWei, Anel Tankovic, Ellington D McDaniels, Rehan Sheikh, Ruth K Mizu, Manish M Karamchandani, Chun Hu, Hirofumi Kusumoto, Joseph Pecha, Gerarda Cappuccio, John Gaitanis, Jennifer Sullivan, Vandana Shashi, Slave Petrovski, Robin-Tobias Jauss, Hyun Kyung Lee, Xiuhua Bozarth, David R Lynch, Ingo Helbig, Tyler Mark Pierson, Cornelius F Boerkoel, Scott J Myers, Johannes R Lemke, Timothy A Benke, Hongjie Yuan, Stephen F Traynelis
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience 14 (5) (2023)
Michael P D'Erasmo, Nicholas S Akins, Peipei Ma, Yao Jing, Sharon A Swanger, Savita K Sharma, Perry W Bartsch, David S Menaldino, Paul J Arcoria, Thi-Thien Bui, Alexandre Pons-Bennaceur, Phuong Le, James P Allen, Elijah Z Ullman, Kelsey A Nocilla, Jing Zhang, Riley E Perszyk, Sukhan Kim, Timothy M Acker, Azmain Taz, Samantha L Burton, Kevin J Coe, Russell G Fritzemeier, Nail Burnashev, Hongjie Yuan, Courtney C Aldrich, Stephen F Traynelis
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N -Methyl-d-aspartate Receptor. ACS chemical neuroscience (2023)
Weiting Tang, Jacob T Beckley, Jin Zhang, Rui Song, Yuchen Xu, Sukhan Kim, Michael C Quirk, Albert J Robichaud, Eva Sarai Diaz, Scott J Myers, James J Doherty, Michael A Ackley, Stephen F Traynelis, Hongjie Yuan
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and molecular life sciences : CMLS 80 (2) (2023)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience 14 (5) (2023)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience 14 (5) (2023)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience 14 (5) (2023)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience (2023)
Scott J Myers, Hongjie Yuan, Riley E Perszyk, Jing Zhang, Sukhan Kim, Kelsey A Nocilla, James P Allen, Jennifer M Bain, Johannes R Lemke, Dennis Lal, Timothy A Benke, Stephen F Traynelis
Classification of missense variants in the N-methyl-D-aspartate receptor GRIN gene family as gain- or loss-of-function. Human molecular genetics (2023)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience 14 (5) (2023)
Chad R Camp, Anna Vlachos, Chiara Klöckner, Ilona Krey, Tue G Banke, Nima Shariatzadeh, Sarah M Ruggiero, Peter Galer, Kristen L Park, Adam Caccavano, Sarah Kimmel, Xiaoqing Yuan, Hongjie Yuan, Ingo Helbig, Tim A Benke, Johannes R Lemke, Kenneth A Pelkey, Chris J McBain, Stephen F Traynelis
Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons. Communications biology 6 (1) (2023)
James P Allen, Kathryn B Garber, Riley Perszyk, Cara T Khayat, Steven A Kell, Maki Kaneko, Catherine Quindipan, Sulagna Saitta, Roger L Ladda, Stacy Hewson, Michal Inbar-Feigenberg, Chitra Prasad, Asuri N Prasad, Leah Olewiler, Weiyi Mu, Liana S Rosenthal, Marcello Scala, Pasquale Striano, Federico Zara, Tyler W McCullock, Robin-Tobias Jauss, Johannes R Lemke, David M MacLean, Cheng Zhu, Hongjie Yuan, Scott J Myers, Stephen F Traynelis
Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants. Human molecular genetics (2023)
Weiting Tang, Jacob T Beckley, Jin Zhang, Rui Song, Yuchen Xu, Sukhan Kim, Michael C Quirk, Albert J Robichaud, Eva Sarai Diaz, Scott J Myers, James J Doherty, Michael A Ackley, Stephen F Traynelis, Hongjie Yuan
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and molecular life sciences : CMLS 80 (2) (2023)
Weiting Tang, Jacob T Beckley, Jin Zhang, Rui Song, Yuchen Xu, Sukhan Kim, Michael C Quirk, Albert J Robichaud, Eva Sarai Diaz, Scott J Myers, James J Doherty, Michael A Ackley, Stephen F Traynelis, Hongjie Yuan
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and molecular life sciences : CMLS 80 (2) (2023)
Rui Song, Jin Zhang, Riley E Perszyk, Chad R Camp, Weiting Tang, Varun Kannan, Jia Li, Yuchen Xu, Jiahui Chen, Yin-Long Li, Steven H Liang, Stephen F Traynelis, Hongjie Yuan
Differential responses of disease-related GRIN variants located in pore-forming M2 domain of N-methyl-D-aspartate receptor to FDA-approved inhibitors. Journal of neurochemistry (2023)
Lingling Xie, Miranda J McDaniel, Riley E Perszyk, Sukhan Kim, Gerarda Cappuccio, Kevin A Shapiro, Beatriz Muñoz-Cabello, Pedro A Sanchez-Lara, Katheryn Grand, Jing Zhang, Kelsey A Nocilla, Rehan Sheikh, Lluis Armengol, Roberta Romano, Tyler Mark Pierson, Hongjie Yuan, Scott J Myers, Stephen F Traynelis
Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening. Cellular and molecular life sciences : CMLS 80 (4) (2023)
Lingling Xie, Miranda J McDaniel, Riley E Perszyk, Sukhan Kim, Gerarda Cappuccio, Kevin A Shapiro, Beatriz Muñoz-Cabello, Pedro A Sanchez-Lara, Katheryn Grand, Jing Zhang, Kelsey A Nocilla, Rehan Sheikh, Lluis Armengol, Roberta Romano, Tyler Mark Pierson, Hongjie Yuan, Scott J Myers, Stephen F Traynelis
Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening. Cellular and molecular life sciences : CMLS 80 (4) (2023)
Jesse E Hanson, Hongjie Yuan, Riley E Perszyk, Tue G Banke, Hao Xing, Ming-Chi Tsai, Frank S Menniti, Stephen F Traynelis
Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2023)
Weiting Tang, Jacob T Beckley, Jin Zhang, Rui Song, Yuchen Xu, Sukhan Kim, Michael C Quirk, Albert J Robichaud, Eva Sarai Diaz, Scott J Myers, James J Doherty, Michael A Ackley, Stephen F Traynelis, Hongjie Yuan
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and molecular life sciences : CMLS 80 (2) (2023)
Lynnea D Harris, Michael C Regan, Scott J Myers, Kelsey A Nocilla, Nicholas S Akins, Yesim A Tahirovic, Lawrence J Wilson, Ray Dingledine, Hiro Furukawa, Stephen F Traynelis, Courtney C Aldrich
Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. ACS chemical neuroscience 14 (5) (2023)
Wenshu XiangWei, Riley E Perszyk, Nana Liu, Yuchen Xu, Subhrajit Bhattacharya, Gil H Shaulsky, Constance Smith-Hicks, Ali Fatemi, Andrew E Fry, Kate Chandler, Tao Wang, Julie Vogt, Julie S Cohen, Alex R Paciorkowski, Annapurna Poduri, Yuehua Zhang, Shuang Wang, Yuping Wang, Qiongxiang Zhai, Fang Fang, Jie Leng, Kathryn Garber, Scott J Myers, Robin-Tobias Jauss, Kristen L Park, Timothy A Benke, Johannes R Lemke, Hongjie Yuan, Yu-Wu Jiang, Stephen F Traynelis
Clinical and functional consequences of GRIA variants in patients with neurological diseases. Cellular and molecular life sciences : CMLS 80 (11) (2023)
Carolina Montanez-Miranda, Riley E Perszyk, Nicholas H Harbin, Jennifer Okalova, Suneela Ramineni, Stephen F Traynelis, John R Hepler
Functional assessment of cancer-linked mutations in sensitive regions of RGS proteins predicted by 3DMTR analysis . Molecular pharmacology (2022)
Riley E Perszyk, Anders S Kristensen, Polina Lyuboslavsky, Stephen F Traynelis
Three-dimensional missense tolerance ratio analysis. Genome research 31 (8) (2021)
Riley E Perszyk, Zhaoshi Zheng, Tue G Banke, Jing Zhang, Lingling Xie, Miranda J McDaniel, Brooke M Katzman, Stephen C Pelly, Hongjie Yuan, Dennis C Liotta, Stephen F Traynelis
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors. Molecular pharmacology 99 (5) (2021)
Yuchen Xu, Rui Song, Wenjuan Chen, Katie Strong, Daniel Shrey, Satyanarayana Gedela, Stephen F Traynelis, Guojun Zhang, Hongjie Yuan
Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy. Annals of clinical and translational neurology 8 (7) (2021)
Riley E Perszyk, Scott J Myers, Hongjie Yuan, Alasdair J Gibb, Hiro Furukawa, Alexander I Sobolevsky, Stephen F Traynelis
Hodgkin-Huxley-Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of physiology 598 (15) (2020)
Juliette Piard, Matthieu Bereau, Wenshu XiangWei, Thomas Wirth, Daniel Amsallem, Lauren Buisson, Philippe Richard, Na-Na Liu, Yuchen Xu, Scott J Myers, Stephen F Traynelis, Jameleddine Chelly, Mathieu Anheim, Martine Raynaud, Lionel Van Maldergem, Hongjie Yuan
The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus. Movement disorders : official journal of the Movement Disorder Society 35 (7) (2020)
Matthew P Epplin, Ayush Mohan, Lynnea D Harris, Zongjian Zhu, Katie L Strong, John Bacsa, Phuong Le, David S Menaldino, Stephen F Traynelis, Courtney C Aldrich
Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) Receptor. Journal of medicinal chemistry 63 (14) (2020)
Katie L Strong, Matthew P Epplin, Kevin K Ogden, Pieter B Burger, Thomas M Kaiser, Timothy J Wilding, Hiro Kusumoto, Chad R Camp, Gil Shaulsky, Subhrajit Bhattacharya, Riley E Perszyk, David S Menaldino, Miranda J McDaniel, Jing Zhang, Phuong Le, Tue G Banke, Kasper B Hansen, James E Huettner, Courtney C Aldrich, Stephen F Traynelis
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors. ACS chemical neuroscience 12 (1) (2020)
Riley E Perszyk, Sharon A Swanger, Chris Shelley, Alpa Khatri, Gabriela Fernandez-Cuervo, Matthew P Epplin, Jing Zhang, Phuong Le, Pernille Bülow, Ethel Garnier-Amblard, Pavan Kumar Reddy Gangireddy, Gary J Bassell, Hongjie Yuan, David S Menaldino, Dennis C Liotta, Lanny S Liebeskind, Stephen F Traynelis
Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature chemical biology 16 (2) (2020)
Hualong Fu, Weiting Tang, Zhen Chen, Vasily V Belov, Genwei Zhang, Tuo Shao, Xiaofei Zhang, Qingzhen Yu, Jian Rong, Xiaoyun Deng, Wei Han, Scott J Myers, Pilar Giffenig, Lu Wang, Lee Josephson, Yihan Shao, April T Davenport, James B Daunais, Mikhail Papisov, Hongjie Yuan, Zijing Li, Stephen F Traynelis, Steven H Liang
Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain. ACS chemical neuroscience 10 (5) (2019)
Jia Li, Jin Zhang, Weiting Tang, Ruth K Mizu, Hirofumi Kusumoto, Wenshu XiangWei, Yuchen Xu, Wenjuan Chen, Johansen B Amin, Chun Hu, Varun Kannan, Stephanie R Keller, William R Wilcox, Johannes R Lemke, Scott J Myers, Sharon A Swanger, Lonnie P Wollmuth, Slavé Petrovski, Stephen F Traynelis, Hongjie Yuan
De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases. Human mutation 40 (12) (2019)
Feng Yi, Subhrajit Bhattacharya, Charles M Thompson, Stephen F Traynelis, Kasper B Hansen
Functional and pharmacological properties of triheteromeric GluN1/2B/2D NMDA receptors. The Journal of physiology 597 (22) (2019)
Elizabeth H Moss, Moritz Armbruster, Lauren A Lau, Mary E Sommer, Zin-Juan Klaft, Sharon A Swanger, Stephen F Traynelis, Stephen J Moss, Farzad Noubary, Jayashree Chadchankar, Chris G Dulla
Tonic Activation of GluN2C/GluN2D-Containing NMDA Receptors by Ambient Glutamate Facilitates Cortical Interneuron Maturation. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (19) (2019)
Kasper B Hansen, Feng Yi, Riley E Perszyk, Hiro Furukawa, Lonnie P Wollmuth, Alasdair J Gibb, Stephen F Traynelis
Structure, function, and allosteric modulation of NMDA receptors. The Journal of general physiology 150 (8) (2018)
Subhrajit Bhattacharya, Yuxian Ma, Amy R Dunn, Joshua M Bradner, Annalisa Scimemi, Gary W Miller, Stephen F Traynelis, Thomas Wichmann
NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate. Journal of neuroscience research 96 (7) (2018)
Gordon Wells, Hongjie Yuan, Miranda J McDaniel, Hirofumi Kusumoto, James P Snyder, Dennis C Liotta, Stephen F Traynelis
The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening. Proteins 86 (12) (2018)
Alasdair J Gibb, Kevin K Ogden, Miranda J McDaniel, Katie M Vance, Steven A Kell, Chris Butch, Pieter Burger, Dennis C Liotta, Stephen F Traynelis
A structurally derived model of subunit-dependent NMDA receptor function. The Journal of physiology 596 (17) (2018)
Riley E Perszyk, Brooke M Katzman, Hirofumi Kusumoto, Steven A Kell, Matthew P Epplin, Yesim A Tahirovic, Rhonda L Moore, David Menaldino, Pieter Burger, Dennis C Liotta, Stephen F Traynelis
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups. eLife 7 (2018)
Shuxi Liu, Liang Zhou, Hongjie Yuan, Marta Vieira, Antonio Sanz-Clemente, John D Badger, Wei Lu, Stephen F Traynelis, Katherine W Roche
A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (15) (2017)
Daniel J Galtieri, Chad M Estep, David L Wokosin, Stephen F Traynelis, Dalton James Surmeier
Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons. eLife 6 (2017)
Sharon A Swanger, Katie M Vance, Timothy M Acker, Sommer S Zimmerman, John O DiRaddo, Scott J Myers, Christoffer Bundgaard, Cara A Mosley, Samantha L Summer, David S Menaldino, Henrik S Jensen, Courtney C Aldrich, Stephen F Traynelis
A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons. ACS chemical neuroscience 9 (2) (2017)
Katie L Strong, Matthew P Epplin, John Bacsa, Christopher J Butch, Pieter B Burger, David S Menaldino, Stephen F Traynelis, Courtney C Aldrich
The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors. Journal of medicinal chemistry 60 (13) (2017)
Sharon A Swanger, Katie M Vance, Jean-François Pare, Florence Sotty, Karina Fog, Yoland Smith, Stephen F Traynelis
NMDA Receptors Containing the GluN2D Subunit Control Neuronal Function in the Subthalamic Nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (48) (2016)
Joan Heller Brown, William A Catterall, P Jeffrey Conn, Stuart G Cull-Candy, Ray Dingledine, T Kendall Harden, Paul A Insel, Graeme Milligan, Stephen F Traynelis
The First 50 Years of Molecular Pharmacology. Molecular pharmacology 88 (1) (2015)

Stephen F Traynelis.css-eqlu8i{font-size:small;padding-left:4px;} (Stephen Traynelis)

Publication Activity (10 Years)

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Stephen F Traynelis (Stephen Traynelis)