Human platelet lysate stimulates neurotrophic properties of human adipose-derived stem cells better than Schwann cell-like cells.

Stefania BrambillaMartino GuiottoEnrica TorrettaIlaria ArmeniaMatteo MorettiCecilia GelfiSilvia PalombellaPietro G di Summa

Published in: Stem cell research & therapy (2023)

All together, our results show that HPL-ASCs were more neurotrophic than SC-ASCs. We highlighted that the HPL triggers an immature neuro-induction state of ASCs, while keeping their stem properties, paving the way for innovative therapies for nerve regeneration.

Keyphrases

endothelial cells
stem cells
induced pluripotent stem cells
pluripotent stem cells
single cell
peripheral nerve
cell therapy
wound healing
mesenchymal stem cells