The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.

Jiajie LiBo LiYong ChengQingong MengLili WeiWei LiJiali ZhangShengfu Huang

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)

TLR4 and NOD2 have unique expression sites in salivary glands, and they may synergistically activate autophagy in salivary glands under conditions of inflammation.

Keyphrases

oxidative stress
toll like receptor
cell death
inflammatory response
endoplasmic reticulum stress
immune response
endothelial cells
signaling pathway
poor prognosis
nuclear factor
innate immune
induced pluripotent stem cells