mLiftOver: harmonizing data across Infinium DNA methylation platforms.

Published in: Bioinformatics (Oxford, England) (2024)

mLiftOver is implemented R and available in the Bioconductor package SeSAMe (version 1.21.13+): https://bioconductor.org/packages/release/bioc/html/sesame.html. Analysis of EPIC and EPICv2 platform-specific bias and high-confidence mapping is available at https://github.com/zhou-lab/InfiniumAnnotationV1/raw/main/Anno/EPICv2/EPICv2ToEPIC_conversion.tsv.gz. The source code is available at https://github.com/zwdzwd/sesame/blob/devel/R/mLiftOver.R under the MIT license.

Keyphrases

dna methylation
high resolution
genome wide
gene expression
electronic health record
high throughput
psychometric properties
machine learning
high density
mass spectrometry
artificial intelligence