Sex Hormones, BDNF, Leptin, and TGF-β1 in Females With IBS: A Pilot Investigation.

Kristen R WeaverChristina M BoulineauxJeffrey M RobinsonKierra ButlerMargaret M HeitkemperWendy A Henderson

Published in: Biological research for nursing (2020)

Elevated estradiol in participants with IBS, and differential patterns of biological and psychological indices between groups, encourages further inquiry on the relevance of sex hormones, BDNF, leptin, and TGF-β1 to symptoms of IBS. Future research endeavors should conduct longitudinal quantification of sex hormones with subjective symptom assessment to facilitate insight on the pathophysiology and female sex bias in IBS.

Keyphrases

irritable bowel syndrome
transforming growth factor
sleep quality
clinical trial
stress induced
randomized controlled trial
physical activity
current status
study protocol
patient reported