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Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records.

Karen HomanRachel SeeleyLouis FisherCarol A RobertsSajida KhatriKatie SmithTony JamiesonVictoria SpeedSebastian BaconAmir MehrkarBrian MackennaBen Goldacre
Published in: BJGP open (2024)
CrCl is not recorded for a substantial number of patients on DOACs. We recommend that national organisations tasked with safety, collectively update guidance on the appropriate weight to use in the Cockcroft-Gault equation, clarify that CrCl is not equivalent to eGFR and work with GP clinical system suppliers to standardise the calculation of CrCl in the EHR.
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