Brian Mackenna (Brian MacKenna)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 57

Top Topics

Coronavirus Disease

Direct Oral Anticoagulants

Top Venues

Wellcome open research

Annals of internal medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Lisa E M Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian C J Bacon, Alex J Walker, Alex J Walker, Brian Mackenna
Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study. JMIR public health and surveillance 10 (2024)
Helen J Curtis, Louis Fisher, David Evans, null null, Sebastian Bacon, Amir Mehrkar, Ben Goldacre, Brian Mackenna
Interpreting pathology test result values with comparators (< , >) in Electronic Health Records research: an OpenSAFELY short data report. Wellcome open research 8 (2024)
Elsie M F Horne, William J Hulme, Edward P K Parker, Ruth H Keogh, Elizabeth J Williamson, Venexia M Walker, Tom M Palmer, Rachel Denholm, Rochelle Knight, Helen J Curtis, Alex J Walker, Colm D Andrews, Amir Mehrkar, Jessica Morley, Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne, null null
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP. Epidemiology (Cambridge, Mass.) 35 (4) (2024)
Elsie M F Horne, William J Hulme, Edward P K Parker, Ruth H Keogh, Elizabeth J Williamson, Venexia M Walker, Tom M Palmer, Rachel Denholm, Rochelle Knight, Helen J Curtis, Alex J Walker, Colm D Andrews, Amir Mehrkar, Jessica Morley, Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne, null null
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP. Epidemiology (Cambridge, Mass.) 35 (4) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology (2024)
Christine Cunningham, Louis Fisher, Christopher Wood, Victoria Speed, Andrew D Brown, Helen Curtis, Rose Higgins, Richard Croker, Ben Fc Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian Cj Bacon, Elizabeth Beech, Kieran S Hand, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Liam C Hart, Chris Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP. BMJ medicine 3 (1) (2024)
Lisa E M Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian C J Bacon, Alex J Walker, Alex J Walker, Brian Mackenna
Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study. JMIR public health and surveillance 10 (2024)
Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian Mackenna, Sarah Finer, null null
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform. PLoS medicine 21 (6) (2024)
Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian Mackenna, Sarah Finer, null null
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform. PLoS medicine 21 (6) (2024)
Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian Mackenna, Sarah Finer, null null
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform. PLoS medicine 21 (6) (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Carol A Roberts, Amir Mehrkar, Sebastian Bacon, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Carol A Roberts, Amir Mehrkar, Sebastian Bacon, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open 8 (2) (2024)
Martina Fonseca, Brian Mackenna, Amir Mehrkar, null null, Caroline E Walters, George Hickman, Jonathan Pearson, Louis Fisher, Peter Inglesby, Sebastian C J Bacon, Simon Davy, William J Hulme, Alex J Walker, Ofra Koffman, Minal Bakhai
The Use of Online Consultation Systems or Remote Consulting in England Characterized Through the Primary Care Health Records of 53 Million People in the OpenSAFELY Platform: Retrospective Cohort Study. JMIR public health and surveillance 10 (2024)
Milan Wiedemann, Victoria Speed, Christine Cunningham, Rose Higgins, Helen J Curtis, Colm D Andrews, Louis Fisher, Lisa Hopcroft, Christopher T Rentsch, Viyaasan Mahalingasivam, Laurie A Tomlinson, Caroline E Morton, Miriam Samuel, Amelia Green, Christopher Wood, Andrew D Brown, Jon Massey, Caroline Walters, Rebecca M Smith, Peter Inglesby, David Evans, Steven Maude, Iain Dillingham, Alex J Walker, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Richard J McManus, Alex J Walker, Brian Mackenna
Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY. Open heart 11 (2) (2024)
Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian Mackenna, Sarah Finer, null null
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform. PLoS medicine 21 (6) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
Lisa E M Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian C J Bacon, Alex J Walker, Alex J Walker, Brian Mackenna
Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study. JMIR public health and surveillance 10 (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Carol A Roberts, Amir Mehrkar, Sebastian Bacon, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Carol A Roberts, Amir Mehrkar, Sebastian Bacon, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open 8 (2) (2024)
Elsie M F Horne, William J Hulme, Edward P K Parker, Ruth H Keogh, Elizabeth J Williamson, Venexia M Walker, Tom M Palmer, Rachel Denholm, Rochelle Knight, Helen J Curtis, Alex J Walker, Colm D Andrews, Amir Mehrkar, Jessica Morley, Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne, null null
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP. Epidemiology (Cambridge, Mass.) 35 (4) (2024)
Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian Mackenna, Sarah Finer, null null
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform. PLoS medicine 21 (6) (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Carol A Roberts, Amir Mehrkar, Sebastian Bacon, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open 8 (2) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
Christine Cunningham, Louis Fisher, Christopher Wood, Victoria Speed, Andrew D Brown, Helen Curtis, Rose Higgins, Richard Croker, Ben Fc Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian Cj Bacon, Elizabeth Beech, Kieran S Hand, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Liam C Hart, Chris Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP. BMJ medicine 3 (1) (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Carol A Roberts, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Sebastian Bacon, Amir Mehrkar, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Carol A Roberts, Amir Mehrkar, Sebastian Bacon, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open 8 (2) (2024)
Karen Homan, Rachel Seeley, Louis Fisher, Carol A Roberts, Sajida Khatri, Katie Smith, Tony Jamieson, Victoria Speed, Sebastian Bacon, Amir Mehrkar, Brian Mackenna, Ben Goldacre
Safety of direct-acting oral anticoagulant (DOAC) prescribing: OpenSAFELY-TPP analysis of 20.5 million adults' electronic health records. BJGP open (2024)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine 176 (5) (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine 176 (5) (2023)
Helen J Curtis, Louis Fisher, David Evans, null null, Sebastian Bacon, Amir Mehrkar, Ben Goldacre, Brian Mackenna
Interpreting pathology test result values with comparators (<, >) in Electronic Health Records research: an OpenSAFELY short data report. Wellcome open research 8 (2023)
Helen J Curtis, Louis Fisher, David Evans, null null, Sebastian Bacon, Amir Mehrkar, Ben Goldacre, Brian Mackenna
Interpreting pathology test result values with comparators (<, >) in Electronic Health Records research: an OpenSAFELY short data report. Wellcome open research 8 (2023)
Amelia C A Green, Helen J Curtis, Rose Higgins, Linda Nab, Viyaasan Mahalingasivam, Rebecca M Smith, Amir Mehrkar, Peter Inglesby, Henry Drysdale, Nicholas J DeVito, Richard Croker, Christopher T Rentsch, Krishnan Bhaskaran, John Tazare, Bang Zheng, Colm D Andrews, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, Louis Fisher, George Hickman, Lisa E M Hopcroft, William J Hulme, Jon Massey, Orla MacDonald, Jessica Morley, Caroline E Morton, Robin Y Park, Alex J Walker, Tom Ward, Milan Wiedemann, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen J W Evans, Alex J Walker, Laurie A Tomlinson, Brian Mackenna
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. BMJ medicine 2 (1) (2023)
Louis Fisher, Helen J Curtis, Richard Croker, Milan Wiedemann, Victoria Speed, Christopher Wood, Andrew Brown, Lisa E M Hopcroft, Rose Higgins, Jon Massey, Peter Inglesby, Caroline E Morton, Alex J Walker, Jessica Morley, Amir Mehrkar, Seb Bacon, George Hickman, Orla Macdonald, Tom Lewis, Marion Wood, Martin Myers, Miriam Samuel, Robin Conibere, Wasim Baqir, Harpreet Sood, Charles Drury, Kiren Collison, Chris Bates, David Evans, Iain Dillingham, Tom Ward, Simon Davy, Rebecca M Smith, William J Hulme, Amelia C A Green, John Parry, Frank Hester, Sam Harper, Jonathan Cockburn, Shaun O'Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Paul Griffiths, Aaron Fowles, Nasreen Parkes, Brian Mackenna, Ben Goldacre
Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults' primary care records in England through OpenSAFELY. eLife 12 (2023)
Amelia C A Green, Helen J Curtis, Rose Higgins, Linda Nab, Viyaasan Mahalingasivam, Rebecca M Smith, Amir Mehrkar, Peter Inglesby, Henry Drysdale, Nicholas J DeVito, Richard Croker, Christopher T Rentsch, Krishnan Bhaskaran, John Tazare, Bang Zheng, Colm D Andrews, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, Louis Fisher, George Hickman, Lisa E M Hopcroft, William J Hulme, Jon Massey, Orla MacDonald, Jessica Morley, Caroline E Morton, Robin Y Park, Alex J Walker, Tom Ward, Milan Wiedemann, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen J W Evans, Alex J Walker, Laurie A Tomlinson, Brian Mackenna
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. BMJ medicine 2 (1) (2023)
Isabella Martus, Brian Mackenna, William Rial, Jon Hayhurst, Georgia C Richards
Private prescribing of controlled opioids in England, 2014-2021: a retrospective observational study. The British journal of general practice : the journal of the Royal College of General Practitioners (2023)
Helen J Curtis, Brian Mackenna, Milan Wiedemann, Louis Fisher, Richard Croker, Caroline E Morton, Peter Inglesby, Alex J Walker, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, George Hickman, David Evans, Tom Ward, Simon Davy, William J Hulme, Orla Macdonald, Robin Conibere, Tom Lewis, Martin Myers, Shamila Wanninayake, Kiren Collison, Charles Drury, Miriam Samuel, Harpreet Sood, Andrea Cipriani, Seena Fazel, Manuj Sharma, Wasim Baqir, Christopher Bates, John Parry, Alex J Walker, null null
OpenSAFELY NHS Service Restoration Observatory 2: changes in primary care clinical activity in England during the COVID-19 pandemic. The British journal of general practice : the journal of the Royal College of General Practitioners (2023)
Louis Fisher, Lisa E M Hopcroft, Sarah Rodgers, James Barrett, Kerry Oliver, Anthony J Avery, Dai Evans, Helen J Curtis, Richard Croker, Orla Macdonald, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, George Hickman, Peter Inglesby, Caroline E Morton, Becky Smith, Tom Ward, William J Hulme, Amelia C A Green, Jon Massey, Alex J Walker, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Shaun O'Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Paul Griffiths, Aaron Fowles, Nasreen Parkes, Alex J Walker, Brian Mackenna
Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using federated analytics. BMJ medicine 2 (1) (2023)
Lisa E M Hopcroft, Jon Massey, Helen J Curtis, Brian Mackenna, Richard Croker, Andrew D Brown, Thomas O'Dwyer, Orla Macdonald, David Evans, Peter Inglesby, Sebastian C J Bacon, Alex J Walker, Alex J Walker
Data-Driven Identification of Unusual Prescribing Behavior: Analysis and Use of an Interactive Data Tool Using 6 Months of Primary Care Data From 6500 Practices in England. JMIR medical informatics 11 (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine 176 (5) (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine (2023)
Helen J Curtis, Louis Fisher, David Evans, null null, Sebastian Bacon, Amir Mehrkar, Ben Goldacre, Brian Mackenna
Interpreting pathology test result values with comparators (<, >) in Electronic Health Records research: an OpenSAFELY short data report. Wellcome open research 8 (2023)
Georgia C Richards, Jeffrey K Aronson, Brian Mackenna, Alex J Walker, Frederick David Richard Hobbs, Carl J Heneghan
Sales of Over-the-Counter Products Containing Codeine in 31 Countries, 2013-2019: A Retrospective Observational Study. Drug safety 45 (3) (2022)
Brian Mackenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Alex J Walker
Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review. JMIR medical informatics 10 (12) (2022)
Elsie M F Horne, William J Hulme, Ruth H Keogh, Tom M Palmer, Elizabeth J Williamson, Edward P K Parker, Amelia C A Green, Venexia M Walker, Alex J Walker, Helen J Curtis, Louis Fisher, Brian Mackenna, Richard Croker, Lisa E M Hopcroft, Robin Y Park, Jon Massey, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Caroline E Morton, George Hickman, Simon Davy, Tom Ward, Iain Dillingham, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose: OpenSAFELY cohort study using linked electronic health records. BMJ (Clinical research ed.) 378 (2022)
Brian Mackenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Alex J Walker
Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review. JMIR medical informatics 10 (12) (2022)
William J Hulme, Elizabeth J Williamson, Amelia C A Green, Krishnan Bhaskaran, Helen I McDonald, Christopher T Rentsch, Anna Schultze, John Tazare, Helen J Curtis, Alex J Walker, Laurie A Tomlinson, Tom M Palmer, Elsie M F Horne, Brian Mackenna, Caroline E Morton, Amir Mehrkar, Jessica Morley, Louis Fisher, Sebastian C J Bacon, David Evans, Peter Inglesby, George Hickman, Simon Davy, Tom Ward, Richard Croker, Rosalind M M Eggo, Angel Yun Wong, Rohini Mathur, Kevin Wing, Harriet J Forbes, Daniel J Grint, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Jonathan A C Sterne, Miguel A Hernán, Alex J Walker
Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY. BMJ (Clinical research ed.) 378 (2022)
Brian Mackenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Alex J Walker
Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review. JMIR medical informatics 10 (12) (2022)
Krishnan Bhaskaran, Christopher T Rentsch, George Hickman, William J Hulme, Anna Schultze, Helen J Curtis, Kevin Wing, Charlotte Warren-Gash, Laurie A Tomlinson, Christopher Bates, Rohini Mathur, Brian Mackenna, Viyaasan Mahalingasivam, Angel Yun Wong, Alex J Walker, Caroline E Morton, Daniel J Grint, Amir Mehrkar, Rosalind M M Eggo, Peter Inglesby, Ian J Douglas, Helen I McDonald, Jonathan Cockburn, Elizabeth J Williamson, David Evans, John Parry, Frank Hester, Sam Harper, Stephen Jw Evans, Sebastian C J Bacon, Liam Smeeth, Alex J Walker
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform. PLoS medicine 19 (1) (2022)
Anna Rowan, Chris Bates, William J Hulme, David Evans, Simon Davy, Nicholas Alexander Kennedy, James Galloway, Kathryn E Mansfield, Katie Bechman, Julian Matthewman, Mark Yates, Jeremy Brown, Anna Schultze, Sam Norton, Alex J Walker, Caroline E Morton, Krishnan Bhaskaran, Christopher T Rentsch, Elizabeth J Williamson, Richard Croker, Seb Bacon, George Hickman, Tom Ward, Amelia Green, Louis Fisher, Helen J Curtis, John Tazare, Rosalind M Eggo, Peter Inglesby, Jonathan Cockburn, Helen I McDonald, Rohini Mathur, Angel Yun Wong, Harriet Forbes, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Liam Smeeth, Laurie A Tomlinson, Charlie W Lees, Stephen J W Evans, Catherine H Smith, Sinéad M Langan, Amir Mehkar, Brian Mackenna, Ben Goldacre
A comprehensive high cost drugs dataset from the NHS in England - An OpenSAFELY-TPP Short Data Report. Wellcome open research 6 (2021)
null null, Helen J Curtis, Brian Mackenna, Alex J Walker, Richard Croker, Amir Mehrkar, Caroline E Morton, Sebastian C J Bacon, George Hickman, Peter Inglesby, Christopher Bates, David Evans, Tom Ward, Jonathan Cockburn, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Elizabeth Williamson, William J Hulme, Laurie A Tomlinson, Rohini Mathur, Henry Drysdale, Rosalind M M Eggo, Angel Yun Wong, Harriet J Forbes, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Liam Smeeth, Alex J Walker
OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic. Open heart 8 (2) (2021)
Samantha A Hollingworth, Georgia C Richards, Brian Mackenna, Alex J Walker
Harnessing medicines data at low cost to deliver better and safer care. Pharmacoepidemiology and drug safety 30 (12) (2021)
Michael Liu, Brian Mackenna, William B Feldman, Alex J Walker, Jerry Avorn, Aaron S Kesselheim, Ben Goldacre
Projected spending for brand-name drugs in English primary care given US prices: a cross-sectional study. Journal of the Royal Society of Medicine 113 (9) (2020)
Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Helen J Curtis, Richard Croker, Alex J Walker
Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care. Journal of medical Internet research 22 (10) (2020)
Alex J Walker, Seb Bacon, Helen Curtis, Richard Croker, Brian Mackenna, Ben Goldacre
Six months on: NHS England needs to focus on dissemination, implementation and audit of its low-priority initiative. Journal of the Royal Society of Medicine 112 (1) (2018)