Increased expression of miR146a dysregulates TLR2-induced HBD2 in airway epithelial cells from patients with COPD.

Hymavathi Reddy-VariYerin KimCharu RajputUmadevi S Sajjan

Published in: ERJ open research (2023)

These results suggest that reduced levels of IRAK-1 due to increased expression of miR146a may contribute to impaired expression of TLR2-induced HBD2 in COPD airway epithelial cells.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
chronic obstructive pulmonary disease
high glucose
inflammatory response
immune response
binding protein
long noncoding rna
diabetic rats
lung function